SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP ELISA Kit: 產品信息
產品名稱SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP ELISA Kit
檢測原理Solid Phase Sandwich ELISA (quantitative)
偶聯物HRP
檢測樣品Serum,Cell supernatant
靈敏度 pg/mL
線性范圍93.75-6000 pg/mL
特異性Recognizes both recombinant and natural 2019-nCoV CoV Nucleocapsid
ELISA 試劑盒（即用型）組分1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
產品概述This SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of 2019-nCoV CoV Nucleocapsid protein in Serum,Cell supernatant . It contains recombinant 2019-nCoV CoV Nucleocapsid, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
運輸方式This ELISA Kit is shipped at ambient temperature.
儲存條件Unopened Kit: Store at 2 - 8℃
Opened/Reconstituted Reagents: Please refer to CoA
SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP ELISA Kit: 圖片
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP ELISA Kit: 別稱
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CoV Nucleocapsid 背景信息
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
研究領域
Microbiology>>Pathogenic microorganism>>viruses>>Animal virus>>RNA virus>>+ssRNA virus>>Coronaviridae>>Coronavirus (CoV)>>CoV viral antigen
參考文獻
1.Van Boheemen S, et al. (2012), MBio. 3(6):e00473-12.
Bisht H. et al., 2004, Proc Natl Acad Sci. 101 (17): 6641-6.
Li W. et al., 2005, Science. 309 (5742): 1864-8.

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