EGFR-D770-N771ins_SVD plasmid vector質(zhì)粒載體

EGFR, the epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase, and activated by binding of
its specific ligand, such as epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The
overexpression or overactivity of EGFR has associated with a number of cancers, including the lung cancer and colon
cancer. The identification of EGFR as a driver gene has led to the rapid development of anticancer therapeutics
agents, including Gefitinib, Erlotinib, Afatinib, Osimertinib (AZD9291) and Cetuximab.


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