ANBL6 BR cell line耐藥細胞株

Cell line name ANBL-6 BR

Comments Population: Caucasian.
Characteristics: Produces Ig lambda.
Characteristics: IL6 dependent.
Selected for resistance to: ChEBI; CHEBI:52717; Bortezomib (Velcade).
Derived from sampling site: Peripheral blood.
Sequence variations Mutation; HGNC; 11998; TP53; Simple; p.Gln331Ter (c.991C>T); ClinVar=VCV000922893; Zygosity=Unspecified (from parent cell line).
Mutation; HGNC; 12033; TRAF3; Simple; p.Tyr425Thrfs*36 (c.1272delC); Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5425 (ANBL-6)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line

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