CHO-K1/VISTA聽New

Description
V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells. VISTA levels are heightened within the tumor microenvironment, in which its blockade can enhance antitumor immune responses in mice. In humans, blockade of the related programmed cell death 1 (PD-1) pathway has shown great potential in clinical immunotherapy trials. Here, we report the structure of human VISTA and examine its function in lymphocyte negative regulation in cancer.
Species Human
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 600 μg/ml G418
Properties
Storage Liquid nitrogen immediately upon receiving
Applications
Binding assay or use as immunogen

Supplier來源:BioVector NTCC Inc.
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