H1L1.1c2 cell line CALUX化學激活熒光素酶表達檢測細胞株

Cell line name H1L1.1c2
Synonyms H1L1.1

Comments Group: Patented cell line.

Biotechnology:

BioVector's H1L1.1c2 Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
Characteristics: Acts through the activation of a luciferase gene under the control of dioxin-response elements (DREs).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from sampling site: Liver.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_0328 (Hepa-1c1c7)
Sex of cell Female
Category Cancer cell line

Publications
PubMed=8812265; DOI=10.1006/faat.1996.0056
Garrison P.M., Tullis K., Aarts J.M.M.J.G., Brouwer A., Giesy J.P., Denison M.S.
Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals.
Fundam. Appl. Toxicol. 30:194-203(1996)

Supplier來源:BioVector NTCC Inc.
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