[Designation名稱] NTCC? ID HCT 116 MLH1(+/-) Cell Line細胞株
BioVector NTCC Inc.

DR cancercelllines; CVCL_HD84
DR Horizon_Discovery; HD+104-006
SY MLH1 (+/-) HCT116; BVEC-E2; Bipartite Vector Exon 9 Corrected clone E2
DR Wikidata; Q54881964
RX PubMed=17082796;
CC Population: Caucasian.
CC Characteristics: HCT 116 has a point mutation C755A in exon 9 of MLH1. This cell line is knockin by homologous recombination of the wild-type MLH1 in 1 of the 2 alleles.
CC Knockout cell: Method=Homologous recombination; HGNC; 7127; MLH1 (Note=1 of 2 alleles).
CC Sequence variation: Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 1101; BRCA2; Simple; p.Ile2675Aspfs*6 (c.8021dupA) (c.8021_8022insA); ClinVar=VCV000267050; Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg24Serfs*20 (c.68dupG) (c.68_69insG) (p.G23fs); Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 3373; EP300; Simple; p.Met1470Cysfs*22 (c.4408delA); Zygosity=Heterozygous (from parent cell line).
[Organism物種來源]
[Disease疾病種類]
[Accession編號] NTCC?-AC CVCL_HD84
[Comments描述]
[Reference參考文獻]
[Category分類]
[Date保藏時間]
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培養(yǎng)方法：
Medium培養(yǎng)基：NTCC? ID HCT 116 MLH1(+/-) Complete Medium
Growth properties形態(tài)：貼壁/懸浮：
Culture Condition培養(yǎng)條件：Temperature溫度: 37°C.
Atmosphere: 95% Air, 5% CO2

Supplier生產廠家: BioVector NTCC質粒載體菌種細胞蛋白抗體基因保藏中心
Website網(wǎng)址：www.biovector.net