Name細胞名稱：NTCC? GM23742 AMYOTROPHIC LATERAL SCLEROSIS 1; ALS1 B-Lymphocyte Cell Line
肌萎縮側索硬化癥 1；肌萎縮側索硬化癥1細胞株
Description描述：Clinically affected; onset of symptoms at age 54 years; difficulty swallowing; dysphonia; atrophy/weakness of tongue and facial muscles; fasciculations involving the extremities; bilateral brisk reflexes; absence of any sensory findings; shortness of breath; EMG nerve conduction studies revealed: reduced sensory nerve action potential amplitudes of bilateral median nerves with prolonged latencies, markedly prolonged distal motor latencies of bilateral median nerves with reduced to borderline normal CMAP amplitudes; conduction velocity proximally is borderline normal to slightly slowed, absent right median and ulnar F-responses while right posterior tibial F-response latency is significantly prolonged, left median F response latency is very much prolonged; needle electromyography results revealed fasciculation potentials in the majority of muscles sampled, increased proportion of high amplitude, long duration, polyphasic units with reduced recruitment pattern, APB muscles reveal disproportionately more denervation; possible coexisting neuropathy, polyradiculopathy in addition to ALS considered due to presence of abnormal sensory nerve conduction velocities and more severely reduced velocities and conduction velocities; subject uses communication/learning device and speech, occupational and physical therapy; positive family history: mother, aunt and first cousin were also affected (not in repository).
Category分類：B-Lymphocyte
ID編號:NTCC?-GM23742
Size/Quantity數量: 1 Flask/2 Vials
Biosafety Level生物安全級別:1
Shipping Info運輸方式: RT/Dry Ice
Storage儲存方式: RT/Liquid Nitrogen
Race: More than one race
Age年齡:56 YR
Gender性別:Male
Cell Type細胞類型: AMYOTROPHIC LATERAL SCLEROSIS 1; ALS1
Affected State:Yes
Product:LCL
Gene:
Mutations突變:
Ethnicity:AMERICAN INDIAN/CAUCASIAN
Family:
Relationship:proband
Karyotype:
Tissue Type組織來源:Blood
Complete Growth Medium完全培養基: BioVector? Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing傳代方法:
Cryopreservation凍存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培養條件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鑒定數據:
References參考文獻:

Supplier供應商:BioVector質粒載體菌株細胞蛋白抗體基因保藏中心
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