Name細胞名稱：NTCC? AG08526 ALZHEIMER DISEASE; AD B-Lymphocyte Cell Line
阿爾茨海默病；廣告細胞株
Description描述：This donor was initially diagnosed as Parkinson's disease because he exhibited a slowing of movements. Within 1 year he developed problems with attention span and memory. Further progression of intellectual impairment necessitated assistance with all activities of daily living. Treatment with anti-Parkinsonian medications did not help motor or intellectual function. EEG revealed general slowing. CSF exam was remarkable for an increase in protein concentration. CT scan demonstrated widened sulci and ventricular dilatation. Autopsy confirmed Alzheimer's disease. The culture was initiated on 11/05/85 by transformation of lymphocytes with Epstein Barr virus. The cells grow in suspension and their morphology is spherical. The culture is a mosaic with karyotype: 45,XY,dic(13;19)(p11.3;q13.4)/46,XY; unbalanced; 8%/92% with 6% of the cells examined showing random chromosome loss and 12% showing random chromosomal aberrations. A skin fibroblast culture from same donor is AG08527A. The legacy karyotype description shown in this Remark may not be representative of the current available product.
Category分類：B-Lymphocyte
ID編號:NTCC?-AG08526
Size/Quantity數量: 1 Flask/2 Vials
Biosafety Level生物安全級別:1
Shipping Info運輸方式: RT/Dry Ice
Storage儲存方式: RT/Liquid Nitrogen
Race: White
Age年齡:61 YR
Gender性別:Male
Cell Type細胞類型: ALZHEIMER DISEASE; AD
Affected State:Yes
Product:LCL
Gene:
Mutations突變:
Ethnicity:GERMAN
Family:2051
Relationship:V-31
Karyotype:45,XY,dic(13;19)(p11.3;q13.4){8}/ 46,XY{92}
Tissue Type組織來源:Blood
Complete Growth Medium完全培養基: BioVector? Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing傳代方法:
Cryopreservation凍存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培養條件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鑒定數據:
References參考文獻:

Supplier供應商:BioVector質粒載體菌株細胞蛋白抗體基因保藏中心
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