BioVector? NTCC? AML-VENETOCLAX維奈克拉耐藥細胞株BioVector?  resistant cell line

Venetoclax is a BH3 mimetic small molecule drug that binds and antagonises the pro-survival protein Bcl-2. Venetoclax has transformed the front-line treatment of elderly unfit AML patients.

Overexpression of anti-apoptotic proteins of the B-cell lymphoma 2 (BCL-2) family, including BCL-2, BCL-extra large (XL), and myeloid cell leukemia-1 (MCL-1), is one of the primary mechanisms hematologic cancers employ to escape cell death signaling. 1 Venetoclax (ABT-199) is a compound that selectively inhibits BCL-2, thereby mimicking the function of BH3-only proteins

Supplier來源:BioVector NTCC Inc.
Email: biovector@163.com
Website網址: http://www.biovector.net