pVSV-XN2 BioVector?泡疹性口炎病毒基因組質粒

BioVector NTCC質粒載體菌株細胞蛋白抗體基因保藏中心

BioVector?pVSV-XN2 is a plasmid that contains the entire genome of the vesicular stomatitis virus (VSV). It is used as a tool in genetic engineering to create recombinant VSV viruses.

Here are some key points about pVSV-XN2:

• Full-length VSV genome: It contains all the genetic information necessary to produce a functional VSV virus.

• Unique restriction sites: It has specific restriction enzyme sites (XhoI and NheI) that allow researchers to insert foreign genes into the VSV genome.

• Transcription signals: These signals control the expression of the VSV genes.

• Used for gene therapy: pVSV-XN2 is often used to create recombinant VSV viruses that express therapeutic genes, such as genes that can kill cancer cells.

Here is a schematic diagram of pVSV-XN2:

pVSVXN2 plasmid

As you can see, the plasmid contains the VSV genome, including the genes for the viral proteins (N, P, M, G, and L), as well as the transcription signals. The unique restriction sites (XhoI and NheI) are located between the G and L genes. This is where foreign genes can be inserted to create recombinant VSV viruses.

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