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首頁 ? KUP5 NTCC?永生化小鼠庫普弗細胞株 BioVector NTCC質(zhì)粒載體菌株細胞蛋白抗體基因保藏中心

KUP5 NTCC?永生化小鼠庫普弗細胞株 BioVector NTCC質(zhì)粒載體菌株細胞蛋白抗體基因保藏中心

  • 價  格:¥99850
  • 貨  號:NTCC?-KUP5
  • 產(chǎn)  地:北京
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NTCC? KUP5永生化小鼠庫普弗細胞株

BioVector NTCC質(zhì)粒載體菌株細胞蛋白抗體基因保藏中心


NTCC? KUP5 is an immortalized mouse Kupffer cell line.

  • Kupffer cells: These are specialized macrophages found in the liver. They play a crucial role in liver function, including:

    • Phagocytosis (engulfing and destroying foreign particles)

    • Immune response

    • Metabolism

    • Iron storage

  • Immortalized: This means the cells can divide indefinitely in culture, making them a valuable tool for research.

  • Origin: KUP5 cells were derived from the liver of a C57BL/6 mouse.

  • Characteristics:

    • Exhibit typical macrophage morphology

    • Express macrophage markers (Mac-1, F4/80)

    • Phagocytic activity

    • Release inflammatory cytokines in response to stimulation

  • Research Applications: KUP5 cells are used in various research areas, including:

    • Liver diseases

    • Immunology

    • Drug metabolism

    • Toxicology

    • Inflammation

By providing a stable and readily available source of Kupffer cells, the KUP5 cell line allows researchers to study the functions of these cells in vitro and gain insights into liver biology and disease.


Image

Establishment of c-myc-immortalized Kupffer cell line from a C57BL/6 mouse  strain - ScienceDirect

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