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首頁 ? ST11-KL64 bla-KPC-2 NTCC?肺炎克雷伯氏菌多藥耐藥株Klebsiella pneumoniae BioVector NTCC質粒載體菌株細胞蛋白抗體基因保藏中心

ST11-KL64 bla-KPC-2 NTCC?肺炎克雷伯氏菌多藥耐藥株Klebsiella pneumoniae BioVector NTCC質粒載體菌株細胞蛋白抗體基因保藏中心

  • 價  格:¥989850
  • 貨  號:NTCC?ST11-KL64 bla-KPC-2
  • 產  地:北京
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ST11-KL64 bla-KPC-2 NTCC?肺炎克雷伯氏菌多藥耐藥株Klebsiella pneumoniae

BioVector NTCC質粒載體菌株細胞蛋白抗體基因保藏中心


ST11-KL64 bla-KPC-2 refers to a specific type of Klebsiella pneumoniae bacterium that is resistant to multiple antibiotics, including carbapenems.

Here's a breakdown:

  • ST11: This refers to the sequence type of the bacteria. It is determined by analyzing specific genes within the bacterial genome. ST11 is a globally disseminated and particularly concerning sequence type of K. pneumoniae due to its high resistance and virulence.

  • KL64: This refers to the capsular type of the bacteria. The capsule is a protective layer that surrounds the bacterial cell and plays a role in virulence and immune evasion.

  • bla-KPC-2: This gene encodes KPC-2, a type of Klebsiella pneumoniae carbapenemase. KPC-2 is an enzyme that inactivates carbapenem antibiotics, a class of drugs that are typically used to treat serious infections caused by K. pneumoniae.

Significance of ST11-KL64 bla-KPC-2:

  • Antibiotic Resistance: These bacteria are resistant to multiple antibiotics, including carbapenems, which are often the last-line treatment options for serious infections. This makes infections caused by ST11-KL64 bla-KPC-2 difficult to treat and can lead to severe outcomes.

  • Global Spread: ST11 is a globally disseminated clone, meaning it has spread widely across different countries and regions.

  • Public Health Threat: The emergence and spread of ST11-KL64 bla-KPC-2 strains pose a significant public health threat due to their high resistance and potential for causing severe infections.

Key Points:

  • ST11-KL64 bla-KPC-2 represents a serious threat due to its antibiotic resistance, virulence, and global spread.

  • Infections caused by these bacteria can be difficult to treat and can have serious consequences.

  • Continuous surveillance and the development of new treatment strategies are crucial to combat the spread of these resistant strains.


Image

Genetic characteristics of clinical carbapenem-resistant Klebsiella  pneumoniae:epidemic ST11 KPC-2-producing strains and non-negligible  NDM-5-producing strains with diverse STs | Scientific Reports

Two outbreak cases involving ST65-KL2 and ST11-KL64 hypervirulent  carbapenem-resistant Klebsiella pneumoniae:similarity and diversity  analysis | Communications Biology

Two recombination events occurred in Klebsiella pneumoniae ST11... |  Download Scientific Diagram

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