Romboutsia ilealis NTCC? strain伊氏隆狀腸球菌

BioVector NTCC質粒載體菌株細胞蛋白抗體基因保藏中心

Romboutsia ilealis is a bacterial species within the Firmicutes phylum, belonging to the Lachnospiraceae family. It is part of the gut microbiota and is found primarily in the intestines of mammals, including humans. The species name "ilealis" suggests that it is particularly associated with the ileum, which is the last part of the small intestine.

Key Characteristics of Romboutsia ilealis:

1. Taxonomy:

   • Genus: Romboutsia

   • Species: ilealis

   • Family: Lachnospiraceae

   • Phylum: Firmicutes

2. Microbial Features:

   • Gram-positive: Like other members of the Firmicutes phylum, R. ilealis is Gram-positive.

   • Anaerobic: It grows under anaerobic conditions, which is typical for many gut-associated microbes.

   • Fermentation: As part of the normal gut microbiota, R. ilealis likely participates in the fermentation of complex carbohydrates, producing short-chain fatty acids (SCFAs) like butyrate, which are important for gut health and have anti-inflammatory effects.

3. Role in the Gut Microbiota:

   • R. ilealis is one of the many microbes present in the intestinal microbiome, specifically in the ileum.

   • It is thought to contribute to the maintenance of gut health by participating in the fermentation of dietary fibers, which leads to the production of beneficial metabolites like SCFAs.

   • It may also interact with other gut bacteria to help maintain a balanced gut microbiome and contribute to immune modulation.

4. Research and Significance:

   • Gut Health and Disease: The specific functions and interactions of R. ilealis within the gut microbiome are still being researched, but similar microbes in the Lachnospiraceae family are implicated in intestinal health. Some species in this family have been shown to play roles in gut inflammation, metabolism, and even in preventing the overgrowth of pathogenic organisms.

   • Probiotic Potential: Given its role in producing SCFAs, especially butyrate, R. ilealis or its close relatives may have potential as probiotic candidates for maintaining or restoring gut health, though more research is needed to confirm its specific health benefits.

5. Clinical Relevance:

   • Some gut microbiota imbalances (dysbiosis) can lead to diseases like inflammatory bowel disease (IBD), and understanding the role of specific microbes like R. ilealis may offer insights into therapeutic strategies.

   • There is ongoing research to explore how specific strains of Lachnospiraceae family members, such as R. ilealis, influence intestinal inflammation, immunity, and overall health.

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