[Designation名稱] NTCC? ID ZR-75-1 XI-39 Cell Line細胞株
BioVector NTCC典型培養物保藏中心

Synonyms: ZR-75-1 [XI-39]
Cross-references: CancerTools; 154585
References identifiers: PubMed=8413311;
References identifiers: PubMed=18351453;
Comments: Population: Caucasian.
Comments: Characteristics: Infected with an amphotropic defective murine retrovirus. Retroviral insertion was used in order to identify genes responsible for estrogen-independence and thus tamoxifen resistant (PubMed=8413311; PubMed=18351453).
Comments: Characteristics: Gene likely to be responsible to resistance in this cell line is BCAR3 (PubMed=18351453).
Comments: Selected for resistance to: ChEBI; CHEBI_41774; Tamoxifen.
Comments: Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
Comments: Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Comments: Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Comments: Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
[Organism物種來源]
[Disease疾病種類]
[Accession編號] NTCC?-Accession Number: NTCC?-CVCL_E4M2
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[Reference參考文獻]
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[Date保藏時間]
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培養方法：
Medium培養基：NTCC? ID ZR-75-1 XI-39 Complete Medium
Growth properties形態：貼壁/懸浮：
Culture Condition培養條件：Temperature溫度: 37°C.
Atmosphere: 95% Air, 5% CO2

Supplier生產廠家: BioVector NTCC質粒載體菌種細胞蛋白抗體基因保藏中心
Website網址：www.biovector.net